Invention Grant
- Patent Title: Flow rate balanced, dynamically adjustable sheath delivery system for flow cytometry
-
Application No.: US16030174Application Date: 2018-07-09
-
Publication No.: US10732088B2Publication Date: 2020-08-04
- Inventor: Daniel Nelson Fox , Nathan Michael Gaskill-Fox
- Applicant: Bio-Rad Laboratories, Inc.
- Applicant Address: US CA Hercules
- Assignee: Bio-Rad Laboratories, Inc.
- Current Assignee: Bio-Rad Laboratories, Inc.
- Current Assignee Address: US CA Hercules
- Agency: Weaver Austin Villeneuve & Sampson LLP
- Main IPC: G01N1/28
- IPC: G01N1/28 ; G01N15/14 ; G01N15/00 ; G01N15/10

Abstract:
Disclosed is a sheath delivery system that uses a continuous flow of sheath fluid into a pressurized internal reservoir that substantially matches the outflow of sheath fluid through the nozzle of a flow cytometer. A substantially constant level of the sheath fluid is maintained. If the sheath fluid level falls below a desired level, or goes above a desired level, a dampened control system is used to reach the desired level. In addition, air pressure in the pressurized internal container is controlled so that an external sheath container can be removed and refilled with additional sheath fluid without stopping the sheath delivery system 100. Differences in pressure are detected by a droplet camera, which measures the droplet breakoff point to determine the pressure of the sheath fluid in the nozzle.
Public/Granted literature
- US20180313742A1 FLOW RATE BALANCED, DYNAMICALLY ADJUSTABLE SHEATH DELIVERY SYSTEM FOR FLOW CYTOMETRY Public/Granted day:2018-11-01
Information query