Methods and apparatus to handle enhanced distributed channel access parameters are disclosed. An example apparatus includes a frame generator to generate a data frame instructing a station to operate using a multi-user enhanced distributed channel access (MU EDCA); a communication scheduler to instruct radio architecture to transmit the data frame to the station; the frame generator to generate a buffer status request requesting a buffer status of the station; and the communication scheduler to: instruct radio architecture to transmit the buffer status request to the station; and when a response to the buffer status request corresponds to a non-null queue, scheduling the station to operate using EDCA.