Invention Grant
- Patent Title: 1,4-disubstituted pyridazine analogs there of and methods for treating SMN-deficiency-related conditions
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Application No.: US16237907Application Date: 2019-01-02
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Publication No.: US10758533B2Publication Date: 2020-09-01
- Inventor: Atwood Kim Cheung , Donovan Noel Chin , Natalie Dales , Aleem Fazal , Timothy Brian Hurley , John Kerrigan , Gary O'Brien , Lei Shu , Robert Sun , Moo Je Sung
- Applicant: Novartis AG
- Applicant Address: CH Basel
- Assignee: NOVARTIS AG
- Current Assignee: NOVARTIS AG
- Current Assignee Address: CH Basel
- Agent Wendy F. Ballard
- Main IPC: C07D401/04
- IPC: C07D401/04 ; C07D401/12 ; C07D401/14 ; C07D403/04 ; C07D403/12 ; C07D405/14 ; A61K31/501 ; A61K31/502 ; A61K31/506 ; A61K31/5377 ; A61K31/551 ; A61K45/06 ; C07D237/20 ; C07D403/10 ; C07D403/14 ; C07D409/14 ; C07D413/14 ; C07D417/14 ; C07D471/04 ; C07D471/08 ; C07D471/10 ; C07D487/04 ; C07D487/10 ; A61K31/41 ; A61K31/427 ; C07D237/06

Abstract:
The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
Public/Granted literature
- US20190358226A1 1,4-DISUBSTITUTED PYRIDAZINE ANALOGS THERE OF AND METHODS FOR TREATING SMN-DEFICIENCY-RELATED CONDITIONS Public/Granted day:2019-11-28
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