Invention Grant
- Patent Title: Lipids and lipid compositions for the delivery of active agents
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Application No.: US16115883Application Date: 2018-08-29
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Publication No.: US10792361B2Publication Date: 2020-10-06
- Inventor: Jeremy Lee Baryza , Rohan Eric John Beckwith , Keith Bowman , Crystal Byers , Tanzina Fazal , Gabriel Grant Gamber , Cameron Chuck-Munn Lee , Ritesh Bhanudasji Tichkule , Chandra Vargeese , Shuangxi Wang , Laura West , Thomas Zabawa , Junping Zhao
- Applicant: Novartis AG
- Applicant Address: CH Basel
- Assignee: NOVARTIS AG
- Current Assignee: NOVARTIS AG
- Current Assignee Address: CH Basel
- Agency: Brinks Gilson & Lione
- Agent Yuezhong Feng
- Main IPC: A61K47/18
- IPC: A61K47/18 ; A61K9/127 ; A61K9/51 ; A61K31/713 ; C07C217/58 ; C07C219/06 ; C07C229/12 ; C07D317/28 ; C07D295/096 ; A61K9/00 ; A61K38/22 ; A61K47/22 ; C07C229/14 ; C07C235/42 ; C07D205/04 ; C07D213/69 ; C07D213/79 ; C12N15/113 ; A61K48/00
Abstract:
This invention provides for a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein R1-R4, L and X are defined herein. The compounds of formula (I) and pharmaceutically acceptable salts thereof are cationic lipids useful in the delivery of biologically active agents to cells and tissues.
Public/Granted literature
- US20180369386A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS Public/Granted day:2018-12-27
Information query
IPC分类:
