Examples described herein provide for an electronic circuit, such as a System-on-Chip (SoC), having a Network-on-Chip (NoC). The NoC is configurable and has capabilities to be partially reconfigured. In an example, a NoC on an integrated circuit is configured. Subsystems on the integrated circuit communicate via the NoC. The NoC is partially reconfigured. A first subset of the NoC is reconfigured during the partial reconfiguration, and a second subset of the NoC is capable of continuing to pass communications uninterruptedly during the partial reconfiguration. After the partial reconfiguration, two or more of the subsystems communicate via the first subset of the NoC.