Invention Grant
- Patent Title: Triazole phenyl compounds as agonists of the APJ receptor
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Application No.: US16347955Application Date: 2017-11-03
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Publication No.: US10906890B2Publication Date: 2021-02-02
- Inventor: Ning Chen , Yinhong Chen , Mikkel V. Debenedetto , Paul John Dransfield , James S. Harvey , Julie Anne Heath , Jonathan Houze , Aarif Yusuf Khakoo , Su-Jen Lai , Zhihua Ma , Nobuko Nishimura , Vatee Pattaropong , Gayathri Swaminath , Wen-Chen Yeh , Charles Kreiman
- Applicant: AMGEN INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: AMGEN INC.
- Current Assignee: AMGEN INC.
- Current Assignee Address: US CA Thousand Oaks
- Agent Bernard P. Friedrichsen
- International Application: PCT/US2017/059834 WO 20171103
- International Announcement: WO2018/093579 WO 20180524
- Main IPC: C07D403/14
- IPC: C07D403/14 ; C07D239/24 ; C07D241/12 ; C07D249/14 ; C07D401/04 ; C07D403/04 ; C07D403/12 ; C07D405/14 ; C07D417/12 ; C07D417/14 ; C07D239/26 ; A61P9/04 ; C07D401/14
Abstract:
Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and may have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures: (I), (II) where the definitions of the variables are provided herein.
Public/Granted literature
- US20190284173A1 TRIAZOLE PHENYL COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR Public/Granted day:2019-09-19
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