Invention Grant
- Patent Title: Affinity-based analytical purification of biotherapeutics for bioprocess monitoring
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Application No.: US15831085Application Date: 2017-12-04
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Publication No.: US10920182B2Publication Date: 2021-02-16
- Inventor: Veena Warikoo , Kevin Brower
- Applicant: Genzyme Corporation
- Applicant Address: US MA Cambridge
- Assignee: Genzyme Corporation
- Current Assignee: Genzyme Corporation
- Current Assignee Address: US MA Cambridge
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Main IPC: C12Q3/00
- IPC: C12Q3/00 ; G01N33/573 ; C07K1/22 ; C12C3/00

Abstract:
The invention as disclosed herein provides a method for purifying a non-antibody protein from solution, comprising a chromatography step wherein the solution is passed over an affinity construct containing an affinity ligand-coupled solid support, wherein the affinity construct is associated with a bioprocess unit operation, and isolating the non-antibody protein from solution.
Public/Granted literature
- US20180155801A1 Affinity-Based Analytical Purification of Biotherapeutics for Bioprocess Monitoring Public/Granted day:2018-06-07
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