Invention Grant
- Patent Title: Antibodies specific for hyperphosphorlated tau for the treatment of ocular diseases
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Application No.: US16475299Application Date: 2018-01-03
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Publication No.: US10995137B2Publication Date: 2021-05-04
- Inventor: Jan Torleif Pedersen , Lars Østergaard Pedersen , Justus Claus Daechsel , Ayodeji Abdur-Rasheed Asuni , Nina Helen Rosenqvist
- Applicant: H. Lundbeck A/S
- Applicant Address: DK Valby
- Assignee: H. Lundbeck A/S
- Current Assignee: H. Lundbeck A/S
- Current Assignee Address: DK Valby
- Agency: Wolf, Greenfield & Sacks, P.C.
- Priority: DKPA201700006 20170104
- International Application: PCT/EP2018/050149 WO 20180103
- International Announcement: WO2018/127519 WO 20180712
- Main IPC: C07K16/18
- IPC: C07K16/18 ; C07K14/435 ; A61K38/00 ; A61K39/00 ; A61P25/28 ; G01N33/68
Abstract:
The present invention is based on antibodies which are both highly specific for hyperphosphorylated pathogenic P-S396 tau and highly specific for labelled sections of the human retina, as well as to methods of using these antibodies and their tau binding fragments in the treatment of retinoid amyloidosis, age related macular degeneration (ARMD), and glaucoma.
Public/Granted literature
- US20190330320A1 ANTIBODIES SPECIFIC FOR HYPERPHOSPHORLATED TAU FOR THE TREATMENT OF OCULAR DISEASES Public/Granted day:2019-10-31
Information query
