Invention Grant
- Patent Title: Prostate-associated antigens and vaccine-based immunotherapy regimens
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Application No.: US16058257Application Date: 2018-08-08
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Publication No.: US11110158B2Publication Date: 2021-09-07
- Inventor: Joseph John Binder , Helen Kim Cho , Michael Robert Dermyer , Karin Ute Jooss , Brian Gregory Pierce , Joyce Tsi Tan , Van To Tsai , James Richard Merson
- Applicant: Pfizer Inc.
- Applicant Address: US NY New York
- Assignee: Pfizer Inc.
- Current Assignee: Pfizer Inc.
- Current Assignee Address: US NY New York
- Agent Austin W. Zhang
- Main IPC: A61K39/00
- IPC: A61K39/00 ; C07K14/47 ; C12N9/48 ; A61K39/39 ; A61K39/395 ; A61K31/404 ; C12N9/64 ; A61K9/00 ; A61K31/7088 ; C07K16/28 ; C07K16/30

Abstract:
The present disclosure provides (a) isolated immunogenic PAA polypeptides; (b) isolated nucleic acid molecules encoding immunogenic PAA polypeptides; (c) vaccine compositions comprising an immunogenic PAA polypeptide or an isolated nucleic acid molecule encoding an immunogenic PAA polypeptide; (d) methods relating to uses of the polypeptides, nucleic acid molecules, and compositions; and (e) vaccine-based immunotherapy regimens which involve co-administration of a vaccine in combination with an immune-suppressive-cell inhibitor and an immune-effector-cell enhancer.
Public/Granted literature
- US20190038728A1 PROSTATE-ASSOCIATED ANTIGENS AND VACCINE-BASED IMMUNOTHERAPY REGIMENS Public/Granted day:2019-02-07
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