An electronic device may include an electronic display and a display pipeline. The electronic display may include multiple pixels to display images based at least in part on pixel data. The display pipeline may receive image data and process the image data to determine the pixel data. The display pipeline may include burn-in compensation circuitry to apply gains to the image data based at least in part on burn-in statistics to generate the pixel data. The gain to be applied to the image data for a pixel of the electronic display is determined by the burn-in compensation circuitry, based at least in part on an emission duty cycle of the pixel, to compensate the image data for the pixel for burn-in related aging of the pixel.