Invention Grant
- Patent Title: Dimeric protein with triple mutations
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Application No.: US14413178Application Date: 2013-07-05
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Publication No.: US11180572B2Publication Date: 2021-11-23
- Inventor: Rob N. De Jong , Frank Beurskens , Paul Parren , Aran Frank Labrijn , Janine Schuurman , Arjen Vlug , Sandra Verploegen
- Applicant: GENMAB B.V.
- Applicant Address: NL Utrecht
- Assignee: GENMAB B.V.
- Current Assignee: GENMAB B.V.
- Current Assignee Address: NL Utrecht
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jane E. Remillard, Esq.; Christopher L. Frank
- Priority: WOPCT/EP2012/063339 20120706,DK201300019 20130110
- International Application: PCT/EP2013/064330 WO 20130705
- International Announcement: WO2014/006217 WO 20140109
- Main IPC: C07K16/00
- IPC: C07K16/00 ; A61K39/395 ; C07K16/28 ; C07K16/30 ; C07K16/40 ; C07K16/32 ; C07K16/10 ; C07K16/36 ; C07K16/12 ; A61K39/00
Abstract:
The present invention relates to dimeric proteins comprising amino acids at three different positions which are different from those present in a human IgG1. Six of said dimeric proteins are capable of forming a hexameric structure in solution.
Public/Granted literature
- US20150175707A1 DIMERIC PROTEIN WITH TRIPLE MUTATIONS Public/Granted day:2015-06-25
Information query
