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公开(公告)号:US11180572B2
公开(公告)日:2021-11-23
申请号:US14413178
申请日:2013-07-05
申请人: GENMAB B.V.
发明人: Rob N. De Jong , Frank Beurskens , Paul Parren , Aran Frank Labrijn , Janine Schuurman , Arjen Vlug , Sandra Verploegen
IPC分类号: C07K16/00 , A61K39/395 , C07K16/28 , C07K16/30 , C07K16/40 , C07K16/32 , C07K16/10 , C07K16/36 , C07K16/12 , A61K39/00
摘要: The present invention relates to dimeric proteins comprising amino acids at three different positions which are different from those present in a human IgG1. Six of said dimeric proteins are capable of forming a hexameric structure in solution.
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公开(公告)号:US20150175707A1
公开(公告)日:2015-06-25
申请号:US14413178
申请日:2013-07-05
申请人: GENMAB B.V.
发明人: Rob N. De Jong , Frank Beurskens , Paul Parren , Aran Frank Labrijn , Janine Schuurman , Arjen Vlug , Sandra Verploegen
摘要: The present invention relates to dimeric proteins comprising amino acids at three different positions which are different from those present in a human IgG1. Six of said dimeric proteins are capable of forming a hexameric structure in solution.
摘要翻译: 本发明涉及包含不同于存在于人IgG1中的三个不同位置的氨基酸的二聚体蛋白质。 所述二聚体蛋白中的六个能够在溶液中形成六聚体结构。
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