Invention Grant
- Patent Title: Mesenchymal stem cells for the treatment of CNS diseases
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Application No.: US16047129Application Date: 2018-07-27
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Publication No.: US11185572B2Publication Date: 2021-11-30
- Inventor: Avinoam Kadouri , Avihay Bar-Ilan , Eldad Melamed , Daniel Offen , Ofer Sadan , Merav Bahat-Stromza
- Applicant: Ramot at Tel-Aviv University Ltd. , BrainStorm Cell Therapeutics Ltd.
- Applicant Address: IL Tel-Aviv; IL Petach-Tikva
- Assignee: Ramot at Tel-Aviv University Ltd.,BrainStorm Cell Therapeutics Ltd.
- Current Assignee: Ramot at Tel-Aviv University Ltd.,BrainStorm Cell Therapeutics Ltd.
- Current Assignee Address: IL Tel-Aviv; IL Petach-Tikva
- Main IPC: A61K38/18
- IPC: A61K38/18 ; A61K35/28 ; C12N5/0775 ; C12N5/079 ; A61P25/28 ; C12N5/077 ; A61K35/12
Abstract:
An isolated human cell is disclosed comprising at least one mesenchymal stem cell phenotype and secreting brain-derived neurotrophic factor (BDNF), wherein a basal secretion of the BDNF is at least five times greater than a basal secretion of the BDNF in a mesenchymal stem cell. Methods of generating same and uses of same are also disclosed.
Public/Granted literature
- US20180333458A1 MESENCHYMAL STEM CELLS FOR THE TREATMENT OF CNS DISEASES Public/Granted day:2018-11-22
Information query
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