Invention Grant
- Patent Title: Modulating human Cas9-specific host immune response
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Application No.: US16632782Application Date: 2018-04-27
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Publication No.: US11208640B2Publication Date: 2021-12-28
- Inventor: Radwa Ewaisha , Samira Kiani , Shayesteh Roshdi Ferdosi , Karen Anderson , Farzaneh Moghadam , Sri Krishna , Mo Reza Ebrahimkhani
- Applicant: Arizona Board of Regents on behalf of Arizona State University
- Applicant Address: US AZ Scottsdale
- Assignee: Arizona Board of Regents on behalf of Arizona State University
- Current Assignee: Arizona Board of Regents on behalf of Arizona State University
- Current Assignee Address: US AZ Scottsdale
- Agency: Quarles & Brady LLP
- International Application: PCT/US2018/029937 WO 20180427
- International Announcement: WO2019/018041 WO 20190124
- Main IPC: C12N9/22
- IPC: C12N9/22 ; G01N33/573 ; A61K48/00
Abstract:
Provided herein are methods and compositions for reducing an undesirable T cell immune response in human patients prior to and/or during gene therapy using CRISPR/Cas9-based genetic modulation.
Public/Granted literature
- US20200377871A1 Modulating Human Cas9-Specific Host Immune Response Public/Granted day:2020-12-03
Information query
