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公开(公告)号：US11208640B2
公开(公告)日：2021-12-28
申请号：US16632782
申请日：2018-04-27
发明人： Radwa Ewaisha , Samira Kiani , Shayesteh Roshdi Ferdosi , Karen Anderson , Farzaneh Moghadam , Sri Krishna , Mo Reza Ebrahimkhani
IPC分类号： C12N9/22 , G01N33/573 , A61K48/00
摘要： Provided herein are methods and compositions for reducing an undesirable T cell immune response in human patients prior to and/or during gene therapy using CRISPR/Cas9-based genetic modulation.
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公开(公告)号：US20200377871A1
公开(公告)日：2020-12-03
申请号：US16632782
申请日：2018-04-27
发明人： Radwa Ewaisha , Samira Kiani , Shayesteh Roshdi Ferdosi , Karen Anderson , Farzaneh Moghadam , Sri Krishna , Mo Reza Ebrahimkhani
IPC分类号： C12N9/22 , G01N33/573
摘要： Provided herein are methods and compositions for reducing an undesirable T cell immune response in human patients prior to and/or during gene therapy using CRISPR/Cas9-based genetic modulation.
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公开(公告)号：US12084691B2
公开(公告)日：2024-09-10
申请号：US17546810
申请日：2021-12-09
发明人： Radwa Ewaisha , Samira Kiani , Shayesteh Roshdi Ferdosi , Karen Anderson , Farzaneh Moghadam , Sri Krishna , Mo Reza Ebrahimkhani
IPC分类号： C12N9/22 , A61K48/00 , G01N33/573
CPC分类号： C12N9/22 , G01N33/573 , A61K48/00 , C12N2310/20 , C12N2800/80 , G01N2333/922
摘要： Provided herein are methods and compositions for reducing an undesirable T cell immune response in human patients prior to and/or during gene therapy using CRISPR/Cas9-based genetic modulation.
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公开(公告)号：US20220162574A1
公开(公告)日：2022-05-26
申请号：US17546810
申请日：2021-12-09
发明人： Samira Kiani , Radwa Ewaisha , Shayesteh Roshdi Ferdosi , Karen Anderson , Farzaneh Moghadam , Sri Krishna , Mohammad R Ebrahimkhani
IPC分类号： C12N9/22 , G01N33/573
摘要： Provided herein are methods and compositions for reducing an undesirable T cell immune response in human patients prior to and/or during gene therapy using CRISPR/Cas9-based genetic modulation.
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