Systems and methods to predict and prefetch a cache access based on a delta pattern are disclosed. The delta pattern may comprise a sequence of differences between first and second cache accesses within a page. In one example, a processor includes execution circuitry to extract a delta history corresponding to a delta pattern associated with one or more previous cache accesses corresponding to a page of memory. The processor execution circuitry further generates a bucketed delta history based on the delta history corresponding to the page of memory and selects a prediction entry based on the bucketed delta history. The processor execution circuitry then identifies one or more prefetch candidates based on a confidence threshold, with the confidence threshold indicating one or more probable delta patterns, and filters the one or more prefetch candidates. Prefetch circuitry of the processor then predicts and prefetches a cache access based the one or more prefetch candidates.