Invention Grant
- Patent Title: Droplet-based surface modification and washing
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Application No.: US16788187Application Date: 2020-02-11
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Publication No.: US11255809B2Publication Date: 2022-02-22
- Inventor: Vamsee K. Pamula , Vijay Srinivasan , Michael G. Pollack , Richard B. Fair
- Applicant: Advanced Liquid Logic, Inc. , Duke University
- Applicant Address: US CA San Diego; US NC Durham
- Assignee: Advanced Liquid Logic, Inc.,Duke University
- Current Assignee: Advanced Liquid Logic, Inc.,Duke University
- Current Assignee Address: US CA San Diego; US NC Durham
- Agency: Illumina, Inc.
- Main IPC: G01N27/26
- IPC: G01N27/26 ; B01F13/00 ; B01L3/00 ; B01L7/00 ; G01N35/00 ; C12Q1/686 ; C12Q1/6869 ; G01N27/447 ; G01N27/327 ; G01N27/416 ; B01L3/02

Abstract:
The present invention relates to droplet-based surface modification and washing. According to one embodiment, a method of splitting a droplet is provided, the method including providing a droplet microactuator including a droplet including one or more beads and immobilizing at least one of the one or more beads. The method further includes conducting one or more droplet operations to divide the droplet to yield a set of droplets including a droplet including the one or more immobilized beads and a droplet substantially lacking the one or more immobilized beads.
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