- Patent Title: Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
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Application No.: US16328449Application Date: 2017-08-25
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Publication No.: US11337970B2Publication Date: 2022-05-24
- Inventor: Emily Charlotte Cherney , Weifang Shan , Liping Zhang , Susheel Jethanand Nara , Audris Huang , James Aaron Balog
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee Address: US NJ Princeton
- Agency: BakerHostetler
- International Application: PCT/US2017/048533 WO 20170825
- International Announcement: WO2018/039512 WO 20180301
- Main IPC: A61K31/4709
- IPC: A61K31/4709 ; A61K31/4375 ; A61K31/5025 ; A61K31/517 ; A61K39/395 ; C07D401/08 ; C07D401/12 ; C07D413/12 ; C07D417/12 ; C07D471/04 ; C07D487/04 ; C07D491/056
Abstract:
There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.
Public/Granted literature
- US20210290613A1 INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE Public/Granted day:2021-09-23
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