Invention Grant
- Patent Title: Structure of GII.4 norovirus protease—design of broad-spectrum protease inhibitors
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Application No.: US16335349Application Date: 2017-10-05
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Publication No.: US11344600B2Publication Date: 2022-05-31
- Inventor: B. Venkataram Prasad , Mary K. Estes , Yongcheng Song
- Applicant: Baylor College of Medicine
- Applicant Address: US TX Houston
- Assignee: Baylor College of Medicine
- Current Assignee: Baylor College of Medicine
- Current Assignee Address: US TX Houston
- Agency: Norton Rose Fulbright US LLP
- International Application: PCT/US2017/055387 WO 20171005
- International Announcement: WO2018/067847 WO 20180412
- Main IPC: A61K38/06
- IPC: A61K38/06 ; A61K31/27 ; A61K31/40 ; A61K31/407 ; A61K38/00 ; A61K45/06 ; A61P31/14 ; G16C20/50 ; G16B15/30 ; A01N47/12 ; C07K5/068 ; C07K5/062 ; C07D295/10 ; A01N47/28 ; A01N47/34 ; C07C201/00 ; C07C271/18 ; C07D498/08 ; A61K9/00 ; A01N43/90 ; C07C271/22 ; A61K31/395 ; A01N43/64 ; A01N37/46
Abstract:
The present disclosure concerns inhibitors of Norovirus protease that are suitable for use against any genotype of Norovirus, including at least GII.4 Norovirus proteases. In particular embodiments, specific compositions are encompassed, including their use for prevention or treatment of Norovirus infection in an individual.
Public/Granted literature
- US20190275101A1 STRUCTURE OF GII.4 NOROVIRUS PROTEASE - DESIGN OF BROAD-SPECTRUM PROTEASE INHIBITORS Public/Granted day:2019-09-12
Information query
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