Invention Grant
- Patent Title: ATF3 induction compounds
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Application No.: US16496376Application Date: 2018-03-22
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Publication No.: US11365200B2Publication Date: 2022-06-21
- Inventor: Heng Lin , Ming-jaw Don , Ching-feng Cheng , Jing-jy Cheng , Wen-shan Li , Hui-chen Ku , Hsiao-fen Li , Hsi-hsien Chen , W J Huang
- Applicant: TAIPEI MEDICAL UNIVERSITY , NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE, MINISTRY OF HEALTH AND WELFARE , ACADEMIA SINICA , BUDDHIST TZU CHI MEDICAL FOUNDATION
- Applicant Address: TW Taipei; TW Taipei; TW Taipei; TW Hualien
- Assignee: TAIPEI MEDICAL UNIVERSITY,NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE, MINISTRY OF HEALTH AND WELFARE,ACADEMIA SINICA,BUDDHIST TZU CHI MEDICAL FOUNDATION
- Current Assignee: TAIPEI MEDICAL UNIVERSITY,NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE, MINISTRY OF HEALTH AND WELFARE,ACADEMIA SINICA,BUDDHIST TZU CHI MEDICAL FOUNDATION
- Current Assignee Address: TW Taipei; TW Taipei; TW Taipei; TW Hualien
- Agency: Duane Morris LLP
- International Application: PCT/CN2018/080086 WO 20180322
- International Announcement: WO2018/171688 WO 20180927
- Main IPC: C07D493/04
- IPC: C07D493/04 ; C07D495/04 ; A61K31/366 ; A61K31/381 ; A61P3/10 ; A61P3/04 ; C07D491/153 ; A23L33/10 ; C07D491/052 ; C07D495/14

Abstract:
The invention relates to compounds for treating and/or preventing obesity and obesity-related disorders. Particularly, the invention provides chromanone derivatives used as ATF3 inducer and for treating and/or preventing obesity and obesity-related disorders such as heart disease, hypertension, hyperlipidemia and diabetes.
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