公开(公告)号：US11365200B2

公开(公告)日：2022-06-21

申请号：US16496376

申请日：2018-03-22

申请人： TAIPEI MEDICAL UNIVERSITY ,  NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE, MINISTRY OF HEALTH AND WELFARE ,  ACADEMIA SINICA ,  BUDDHIST TZU CHI MEDICAL FOUNDATION

发明人： Heng Lin ,  Ming-jaw Don ,  Ching-feng Cheng ,  Jing-jy Cheng ,  Wen-shan Li ,  Hui-chen Ku ,  Hsiao-fen Li ,  Hsi-hsien Chen ,  W J Huang

IPC分类号： C07D493/04 ,  C07D495/04 ,  A61K31/366 ,  A61K31/381 ,  A61P3/10 ,  A61P3/04 ,  C07D491/153 ,  A23L33/10 ,  C07D491/052 ,  C07D495/14

摘要： The invention relates to compounds for treating and/or preventing obesity and obesity-related disorders. Particularly, the invention provides chromanone derivatives used as ATF3 inducer and for treating and/or preventing obesity and obesity-related disorders such as heart disease, hypertension, hyperlipidemia and diabetes.