- 专利标题： Treatment of Sirtuin (SIRT) related diseases by inhibition of natural antisense transcript to a Sirtuin (SIRT)
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申请号： US14741164申请日： 2015-06-16
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公开(公告)号： US11408004B2公开(公告)日： 2022-08-09
- 发明人: Joseph Collard , Olga Khorkova Sherman , Carlos Coito , Belinda De Leon
- 申请人： CuRNA, Inc.
- 申请人地址： US FL Miami
- 专利权人： CuRNA, Inc.
- 当前专利权人： CuRNA, Inc.
- 当前专利权人地址： US FL Miami
- 代理机构： Goodwin Procter LLP
- 主分类号： C12N15/11
- IPC分类号： C12N15/11 ; C12N15/113 ; A61K31/7088
摘要：
The present invention relates to antisense oligonucleotide that modulate the expression of and/or function of a Sirtuin (SIRT), in particular, by targeting natural antisense polynucleotides of a Sirtuin (SIRT). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of Sirtuins (SIRT)s.
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