Systems and methods for precision control of microresonator (MR) based frequency combs can implement optimized MR actuators or MR modulators to control long-term locking of carrier envelope offset frequency, repetition rate, or resonance offset frequency of the MR. MR modulators can also be used for amplitude noise control. MR parameters can be locked to external reference frequencies such as a continuous wave laser or a microwave reference. MR parameters can be selected to reduce cross talk between the MR parameters, facilitating long-term locking. The MR can be locked to an external two wavelength delayed self-heterodyne interferometer for low noise microwave generation. An MR-based frequency comb can be tuned by a substantial fraction or more of the free spectral range (FSR) via a feedback control system. Scanning MR frequency combs can be applied to dead-zone free spectroscopy, multi-wavelength LIDAR, high precision optical clocks, or low phase noise microwave sources.