Embodiments are directed towards controlling uncontrolled release of ammonia from an engine of a vehicle. An estimated status of the engine is determined prior to an event, such as an estimated load on the engine prior to the vehicle going up a hill. A predictive model of uncontrolled ammonia release is generated for the estimated status. At least one engine-related countermeasure is selected based on the predictive model. If the predictive model of uncontrolled ammonia release with the selected countermeasures satisfies a threshold condition, then the selected engine-related countermeasure is employed.