- 专利标题: Saponin compound targeting PD-1 and application thereof
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申请号: US16630309申请日: 2018-07-12
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公开(公告)号: US11464795B2公开(公告)日: 2022-10-11
- 发明人: Honglin Li , Weilie Xiao , Lili Zhu , Lina Quan , Qiao Li , Yanyan Diao , Zhenjiang Zhao , Hualiang Jiang
- 申请人: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY , YUNNAN UNIVERSITY , SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
- 申请人地址: CN Shanghai; CN Kunming; CN Shanghai
- 专利权人: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY,YUNNAN UNIVERSITY,SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
- 当前专利权人: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY,YUNNAN UNIVERSITY,SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
- 当前专利权人地址: CN Shanghai; CN Kunming; CN Shanghai
- 代理机构: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- 优先权: CN201710570889.0 20170713
- 国际申请: PCT/CN2018/095426 WO 20180712
- 国际公布: WO2019/011293 WO 20190117
- 主分类号: A61K31/704
- IPC分类号: A61K31/704 ; A61P35/00 ; A61K31/56
摘要:
Provided are use of a saponin compound of formula (I) or (II), or a pharmaceutically acceptable salt, prodrug or solvate thereof, in the manufacture of a medicament targeting PD-1. The medicament targeting PD-1 is one which treats a disease by inhibiting PD-1 from binding to a ligand thereof. The disease may be a tumor, an infection caused by a bacterium, a virus or a fungus, or an inflammatory disease.
公开/授权文献
- US20200163983A1 SAPONIN COMPOUND TARGETING PD-1 AND APPLICATION THEREOF 公开/授权日:2020-05-28
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