- 专利标题： Structured substrates for improving detection of light emissions and methods relating to the same
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申请号： US17247731申请日： 2020-12-21
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公开(公告)号： US11466268B2公开(公告)日： 2022-10-11
- 发明人: M. Shane Bowen , Dajun Yuan
- 申请人： Illumina, Inc.
- 申请人地址： US CA San Diego
- 专利权人： Illumina, Inc.
- 当前专利权人： Illumina, Inc.
- 当前专利权人地址： US CA San Diego
- 代理机构： Illumina, Inc.
- 主分类号： C12N15/10
- IPC分类号： C12N15/10 ; B82Y15/00 ; B82Y20/00 ; G03F7/00 ; G01N21/64 ; B82Y40/00 ; B82Y30/00 ; C12Q1/6874 ; C12Q1/6816 ; C12Q1/6818 ; C12Q1/6869 ; G01N21/76 ; G01N21/05
摘要：
A structured substrate includes a substrate body having an active side. The substrate body includes reaction cavities that open along the active side and interstitial regions that separate the reaction cavities. The structured substrate includes an ensemble amplifier positioned within each of the reaction cavities. The ensemble amplifier includes a plurality of nanostructures configured to at least one of amplify electromagnetic energy that propagates into the corresponding reaction cavity or amplify electromagnetic energy that is generated within the corresponding reaction cavity.
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