Invention Grant
- Patent Title: Neuronal modulation
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Application No.: US16834323Application Date: 2020-03-30
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Publication No.: US11471453B2Publication Date: 2022-10-18
- Inventor: Asya Rolls , Tamar Ben Shannan , Hilla Azulay-Debbie , Fahed Hakim , Maya Schiller , Shai Shen-Orr , Elina Starosvetsky
- Applicant: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED , HEALTH CORPORATION—RAMBAM
- Applicant Address: IL Haifa; IL Haifa
- Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED,HEALTH CORPORATION—RAMBAM
- Current Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED,HEALTH CORPORATION—RAMBAM
- Current Assignee Address: IL Haifa; IL Haifa
- Agency: The Roy Gross Law Firm, LLC
- Agent Roy Gross
- Main IPC: A61N2/00
- IPC: A61N2/00 ; A61N2/02 ; A61K31/48 ; A61K31/428 ; A61K31/473 ; A61K31/506 ; A61K31/404 ; A61K31/4045

Abstract:
A method for modulating an immune response by activating or inhibiting dopaminergic neurons in the Ventral Tegmental Area (VTA) is provided. Modulation is achieved by modulating the activity, the abundance or both of: a natural killer cell, a CD8 T-cell, a CD4 T-cell, a B-cell, a dendritic cell, a macrophage, a granulocyte, or their combination.
Public/Granted literature
- US20200246329A1 NEURONAL MODULATION Public/Granted day:2020-08-06
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