Invention Grant
- Patent Title: Solid reagent containment unit, in particular for a portable microfluidic device for sample preparation and molecule analysis
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Application No.: US16226590Application Date: 2018-12-19
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Publication No.: US11511278B2Publication Date: 2022-11-29
- Inventor: Marco Cereda , Lillo Raia , Alessandro Paolo Bramanti
- Applicant: STMICROELECTRONICS S.R.L.
- Applicant Address: IT Agrate Brianza
- Assignee: STMICROELECTRONICS S.R.L.
- Current Assignee: STMICROELECTRONICS S.R.L.
- Current Assignee Address: IT Agrate Brianza
- Agency: Seed IP Law Group LLP
- Priority: IT102017000150564 20171228
- Main IPC: B01L3/00
- IPC: B01L3/00 ; C12N15/10 ; B29C43/18 ; B01L9/00 ; B29C43/14 ; B29L31/00 ; B29C43/02

Abstract:
A solid reagent containment unit is formed by a support; a frame body fixed to the support and delimiting internally, together with the support, an analysis volume; a reagent-adhesion structure within the analysis volume; and at least one reagent cavity, which extends within the reagent-adhesion structure. The reagent-adhesion structure is of an adhesion material embossable at temperatures lower by 6-8° C. than its own melting point and has a melting point such as not to interfere with the analysis. The reagent cavity forms a retention wall, laterally surrounding the reagent cavity, and houses dried reagents. The adhesion material is chosen among wax, such as paraffin, a polymer, such as polycaprolactone, a solid fat, such as cocoa butter, and a gel, such as hydrogel or organogel.
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