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公开(公告)号：US11491489B2
公开(公告)日：2022-11-08
申请号：US16231272
申请日：2018-12-21
摘要： A microfluidic group includes a female connector and a male needle connector. The female connector has a connector chamber in a containment body; a duct extending in the containment body to a duct opening on a first face of the connector chamber; a needle entry hole extending from a lateral face of the containment body to a second face, not facing the first face of the connector chamber; and a gasket arranged in the connector chamber. The gasket has a side wall internally delimiting a cavity and extending in part adjacent to the second face of the connector chamber. The cavity of the gasket faces the first face of the connector chamber.
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公开(公告)号：US12017222B2
公开(公告)日：2024-06-25
申请号：US17465732
申请日：2021-09-02
发明人： Marco Cereda , Lillo Raia , Danilo Pirola
IPC分类号： B01L3/00 , A61B5/15 , A61B5/154 , B01F33/30 , B01F33/40 , B01F33/452 , B01L9/00 , C12M3/06 , C12Q1/6806 , C12Q1/6844
CPC分类号： B01L3/502753 , A61B5/15003 , A61B5/150221 , A61B5/150351 , A61B5/154 , B01F33/30 , B01F33/406 , B01F33/452 , B01L3/502715 , B01L3/502723 , B01L3/50273 , B01L3/502738 , B01L3/5029 , B01L3/508 , B01L3/5082 , B01L3/52 , B01L3/527 , B01L9/527 , C12M23/16 , A61B5/150389 , A61B5/150503 , A61B5/150732 , B01L3/5023 , B01L3/502707 , B01L3/50825 , B01L3/523 , B01L2200/025 , B01L2200/026 , B01L2200/0621 , B01L2200/0642 , B01L2200/0668 , B01L2200/0673 , B01L2200/0689 , B01L2200/10 , B01L2200/141 , B01L2200/16 , B01L2300/022 , B01L2300/023 , B01L2300/044 , B01L2300/0609 , B01L2300/0681 , B01L2300/08 , B01L2300/0816 , B01L2300/0819 , B01L2300/0829 , B01L2300/0848 , B01L2300/0851 , B01L2300/0858 , B01L2300/0864 , B01L2300/087 , B01L2300/12 , B01L2300/16 , B01L2300/1827 , B01L2400/04 , B01L2400/0406 , B01L2400/043 , B01L2400/0487 , B01L2400/049 , B01L2400/0677 , C12Q1/6806 , C12Q1/6844 , C12Q1/6806 , C12Q2565/629 , C12Q1/6844 , C12Q2565/629
摘要： An analysis unit formed by an analysis body housing an analysis chamber and having a sample inlet and a supply channel configured to fluidically connect the sample inlet to the analysis chamber. Dried assay reagents are arranged in the analysis chamber and are contained in an alveolar mass. For instance, the alveolar mass is a lyophilized mass formed by excipients and by assay-specific reagents.
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公开(公告)号：US11278897B2
公开(公告)日：2022-03-22
申请号：US16224626
申请日：2018-12-18
发明人： Davide Cucchi , Marco Angelo Bianchessi , Alessandro Cocci , Lillo Raia , Lorenzo Bruno , Nadia Serina , Marco Cereda , Danilo Pirola , Pietro Ferrari , Francesco Ferrara , Alessandro Paolo Bramanti
IPC分类号： B01L3/00 , C12Q1/6806 , G01N1/34
摘要： A sample treatment and molecule analysis cartridge is configured to be mounted in a treatment machine vertically. The cartridge has a sample inlet opening, a fluidic inlet, and a fluidic outlet. The cartridge houses an extraction chamber extending vertically from the sample inlet opening and connected to the fluidic inlet; a waste chamber extending vertically, alongside the extraction chamber; and a collector extending along the extraction chamber and the waste chamber and having a smaller height than the extraction chamber and the waste chamber. A fluidic circuit connects together the extraction chamber, the waste chamber, the collector, the fluidic inlet, and the fluidic outlet, and is configured to connect the fluidic outlet to vent openings of the extraction chamber, the waste chamber, and the collector, and to connect the bottom end of the extraction chamber to the fluidic inlet, the waste chamber, and the collector.
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公开(公告)号：US11511278B2
公开(公告)日：2022-11-29
申请号：US16226590
申请日：2018-12-19
摘要： A solid reagent containment unit is formed by a support; a frame body fixed to the support and delimiting internally, together with the support, an analysis volume; a reagent-adhesion structure within the analysis volume; and at least one reagent cavity, which extends within the reagent-adhesion structure. The reagent-adhesion structure is of an adhesion material embossable at temperatures lower by 6-8° C. than its own melting point and has a melting point such as not to interfere with the analysis. The reagent cavity forms a retention wall, laterally surrounding the reagent cavity, and houses dried reagents. The adhesion material is chosen among wax, such as paraffin, a polymer, such as polycaprolactone, a solid fat, such as cocoa butter, and a gel, such as hydrogel or organogel.
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公开(公告)号：US11110457B2
公开(公告)日：2021-09-07
申请号：US16221152
申请日：2018-12-14
发明人： Marco Cereda , Lillo Raia , Danilo Pirola
IPC分类号： B01L3/00 , C12M3/06 , A61B5/15 , B01F13/00 , B01L9/00 , A61B5/154 , B01F13/08 , B01F13/02 , C12Q1/6844 , C12Q1/6806
摘要： An analysis unit formed by an analysis body housing an analysis chamber and having a sample inlet and a supply channel configured to fluidically connect the sample inlet to the analysis chamber. Dried assay reagents are arranged in the analysis chamber and are contained in an alveolar mass. For instance, the alveolar mass is a lyophilized mass formed by excipients and by assay-specific reagents.
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