Invention Grant
- Patent Title: Compositions and methods for cellular reprogramming
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Application No.: US16982964Application Date: 2019-03-21
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Publication No.: US11512290B2Publication Date: 2022-11-29
- Inventor: Conrad Hodgkinson , Victor Dzau , Jaewoo Lee , Bruce A. Sullenger
- Applicant: Duke University
- Applicant Address: US NC Durham
- Assignee: Duke University
- Current Assignee: Duke University
- Current Assignee Address: US NC Durham
- Agency: Quarles & Brady LLP
- International Application: PCT/US2019/023461 WO 20190321
- International Announcement: WO2019/183415 WO 20190926
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C12N5/077 ; A61K31/713 ; C12N15/113
Abstract:
Disclosed herein are compositions and methods for cellular reprogramming. The compositions comprise one or more miRs and an activator of NFκB. Also provided are methods for enhancing or upregulating cardiomyocyte maturation in a cell or a subject and methods for inhibiting or downregulating cardiomyocyte maturation.
Public/Granted literature
- US20210017497A1 COMPOSITIONS AND METHODS FOR CELLULAR REPROGRAMMING Public/Granted day:2021-01-21
Information query
