Invention Grant
- Patent Title: Naphthyridinone derivatives and their use in the treatment of arrhythmia
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Application No.: US17071311Application Date: 2020-10-15
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Publication No.: US11530213B2Publication Date: 2022-12-20
- Inventor: Guillaume Barbe , Gregory Raymond Bebernitz , Sicong Geng , Hatice Belgin Gulgeze Efthymiou , Lv Liao , Fupeng Ma , Ruowei Mo , David Thomas Parker , Yunshan Peng , Stefan Peukert , Nichola Smith , Ken Yamada , Kayo Yasoshima
- Applicant: NOVARTIS AG
- Applicant Address: CH Basel
- Assignee: NOVARTIS AG
- Current Assignee: NOVARTIS AG
- Current Assignee Address: CH Basel
- Agent Timothy P. O'Dea
- Priority: WOPCT/CN2016/102928 20161021
- Main IPC: A61P9/00
- IPC: A61P9/00 ; A61P9/06 ; C07D471/04 ; A61K31/4375 ; A61K31/496 ; A61K31/5377 ; A61K31/541 ; A61K31/675 ; A61K45/06 ; C07F9/6561

Abstract:
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; Wherein R1, R3-R6, X2 and X3 are as defined herein, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
Public/Granted literature
- US20210284635A1 NOVEL NAPHTHYRIDINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF ARRHYTHMIA Public/Granted day:2021-09-16
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