Invention Grant
![1H-pyrazolo[4,3-d]pyrimidine compounds as toll-like receptor 7 (TLR7) agonists and methods and uses therefor](/docs/US/2023-01-17/US11554120B2/abs.jpg.600x600.jpg)
- Patent Title: 1H-pyrazolo[4,3-d]pyrimidine compounds as toll-like receptor 7 (TLR7) agonists and methods and uses therefor
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Application No.: US16527802Application Date: 2019-07-31
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Publication No.: US11554120B2Publication Date: 2023-01-17
- Inventor: Yam B. Poudel , Sanjeev Gangwar , Liqi He , Prasanna Sivaprakasam , Matthias Broekema , Matthew Cox , Christine M. Tarby , Qian Zhang , Naidu S. Chowdari
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee Address: US NJ Princeton
- Agent Joseph F. Reidy; Yuan Chao
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/519 ; A61K47/60 ; A61K39/395 ; A61P35/00 ; A61K31/395
![1H-pyrazolo[4,3-d]pyrimidine compounds as toll-like receptor 7 (TLR7) agonists and methods and uses therefor](/abs-image/US/2023/01/17/US11554120B2/abs.jpg.150x150.jpg)
Abstract:
Compounds according to formula I are useful as agonists of Toll-like receptor 7 (TLR7). Such compounds can be used in cancer treatment, especially in combination with an anti-cancer immunotherapy agent, or as a vaccine adjuvant.
Public/Granted literature
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