Invention Grant
- Patent Title: Mutant Nicotiana benthamiana plant or cell with reduced XylT and FucT
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Application No.: US17098210Application Date: 2020-11-13
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Publication No.: US11576317B2Publication Date: 2023-02-14
- Inventor: Luc Mathis , Daniel F. Voytas , Jin Li , Feng Zhang , Thomas Stoddard , Marc-Andre D'Aoust
- Applicant: CELLECTIS SA , MEDICAGO INC.
- Applicant Address: FR Paris; CA Quebec
- Assignee: CELLECTIS SA,MEDICAGO INC.
- Current Assignee: CELLECTIS SA,MEDICAGO INC.
- Current Assignee Address: FR Paris; CA Quebec
- Agency: Ballard Spahr LLP
- Main IPC: A01H1/06
- IPC: A01H1/06 ; A01H6/82 ; A01H5/12 ; C12N15/82 ; C12N15/01 ; C12N9/22 ; C12P21/00
Abstract:
Materials and methods are provided for making plants (e.g., Nicotiana varieties) that are suitable for producing therapeutic polypeptides suitable for administration to humans and animals, particularly by making TAL effector endonuclease-induced mutations in genes encoding xylosyltransferases and fucosyltransferases.
Public/Granted literature
- US20210059142A1 PLANTS FOR PRODUCTION OF THERAPEUTIC PROTEINS Public/Granted day:2021-03-04
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