- Patent Title: Chromatographic columns and separation devices comprising a superficially porous material; and use thereof for supercritical fluid chromatography and other chromatography
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Application No.: US14897584Application Date: 2014-06-10
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Publication No.: US11577179B2Publication Date: 2023-02-14
- Inventor: Kevin D. Wyndham , Jacob N. Fairchild , Pamela C. Iraneta , Stephen J. Shiner , Darryl W. Brousmiche , Daniel P. Walsh
- Applicant: Waters Technologies Corporation
- Applicant Address: US MA Milford
- Assignee: Waters Technologies Corporation
- Current Assignee: Waters Technologies Corporation
- Current Assignee Address: US MA Milford
- Agency: Womble Bond Dickinson (US) LLP
- Agent Deborah M. Vernon
- International Application: PCT/US2014/041765 WO 20140610
- International Announcement: WO2014/201033 WO 20141218
- Main IPC: B01D15/08
- IPC: B01D15/08 ; B01J20/28 ; B01D15/32 ; B01D15/40 ; B01J20/286 ; B01J20/283 ; B01D15/30 ; B01J20/32 ; C07F7/12 ; C07F7/18
Abstract:
The present invention provides methods for performing supercritical fluid chromatography comprising loading a sample to be separated by supercritical fluid chromatography onto a stationary phase comprising a spherical, monodisperse, core-shell particulate material comprising a nonporous core and one or more layers of a porous shell material surrounding the core, wherein the particles are sized less than 2 microns; and performing supercritical fluid chromatography to separate the sample.
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