- 专利标题： Polyethylene glycol-conjugated glucocorticoid prodrugs and compositions and methods thereof
-
申请号： US17188309申请日： 2021-03-01
-
公开(公告)号： US11583541B2公开(公告)日： 2023-02-21
- 发明人: Dong Wang , Fang Yuan , Zhenshan Jia , Xiaobei Wang
- 申请人： Board of Regents of the University of Nebraska
- 申请人地址： US NE Lincoln
- 专利权人： Board of Regents of the University of Nebraska
- 当前专利权人： Board of Regents of the University of Nebraska
- 当前专利权人地址： US NE Lincoln
- 代理机构： Fox Rothschild LLP
- 主分类号： A61K31/57
- IPC分类号： A61K31/57 ; C07J41/00 ; A61K9/107 ; A61K47/10 ; A61K47/34 ; C07J51/00
摘要：
Polyethylene glycol (PEG)-conjugated glucocorticoid prodrugs, methods of preparation, and use for the treatment of diseases and disorders are disclosed. In particular, PEG-conjugated dexamethasone compounds and methods of using them for treating inflammatory and autoimmune diseases, including but not limited to lupus, are disclosed.
公开/授权文献
信息查询
