-
1.发明申请公开(公告)号：US20200085842A1
公开(公告)日：2020-03-19
申请号：US16694722
申请日：2019-11-25
Inventor： Dong Wang , Fang Yuan , Zhenshan Jia , Xiaobei Wang
Abstract: Polyethylene glycol (PEG)-conjugated glucocorticoid prodrugs, methods of preparation, and use for the treatment of diseases and disorders are disclosed. In particular, PEG-conjugated dexamethasone compounds and methods of using them for treating inflammatory and autoimmune diseases, including but not limited to lupus, are disclosed.
-
2.发明授权公开(公告)号：US12011450B2
公开(公告)日：2024-06-18
申请号：US18172024
申请日：2023-02-21
Inventor： Dong Wang , Fang Yuan , Zhenshan Jia , Xiaobei Wang
CPC classification number: A61K31/57 , A61K9/1075 , A61K47/10 , A61K47/34 , C07J41/0005 , C07J41/0016 , C07J51/00
Abstract: Polyethylene glycol (PEG)-conjugated glucocorticoid prodrugs, methods of preparation, and use for the treatment of diseases and disorders are disclosed. In particular, PEG-conjugated dexamethasone compounds and methods of using them for treating inflammatory and autoimmune diseases, including but not limited to lupus, are disclosed.
-
3.发明授权公开(公告)号：US10933071B2
公开(公告)日：2021-03-02
申请号：US16694722
申请日：2019-11-25
Inventor： Dong Wang , Fang Yuan , Zhenshan Jia , Xiaobei Wang
Abstract: Polyethylene glycol (PEG)-conjugated glucocorticoid prodrugs, methods of preparation, and use for the treatment of diseases and disorders are disclosed. In particular, PEG-conjugated dexamethasone compounds and methods of using them for treating inflammatory and autoimmune diseases, including but not limited to lupus, are disclosed.
-
4.发明公开公开(公告)号：US20240000800A1
公开(公告)日：2024-01-04
申请号：US18172024
申请日：2023-02-21
Inventor： Dong Wang , Fang Yuan , Zhenshan Jia , Xiaobei Wang
CPC classification number: A61K31/57 , C07J41/0016 , C07J41/0005 , A61K9/1075 , A61K47/10 , A61K47/34 , C07J51/00
Abstract: Polyethylene glycol (PEG)-conjugated glucocorticoid prodrugs, methods of preparation, and use for the treatment of diseases and disorders are disclosed. In particular, PEG-conjugated dexamethasone compounds and methods of using them for treating inflammatory and autoimmune diseases, including but not limited to lupus, are disclosed.
-
5.发明申请公开(公告)号：US20220008543A1
公开(公告)日：2022-01-13
申请号：US17288814
申请日：2019-10-27
Inventor： Dong Wang , Steven R. Goldring , Gang Zhao , Rongguo Ren , Zhenshan Jia , Xin Wei
Abstract: This application discloses prodrug-based thermosensitive gel (“ProGel”) comprised of conjugates of dmg molecules with water-soluble polymeric carriers, which are capable of controlled release of the dmg molecules into the tissue of a subject. Use of the ProGel-Drug conjugates for treatment of various diseases or disorders and methods of preparing them are also disclosed.
-
Patent Agency Ranking
6.发明授权公开(公告)号：US11583541B2
公开(公告)日：2023-02-21
申请号：US17188309
申请日：2021-03-01
Inventor： Dong Wang , Fang Yuan , Zhenshan Jia , Xiaobei Wang
Abstract: Polyethylene glycol (PEG)-conjugated glucocorticoid prodrugs, methods of preparation, and use for the treatment of diseases and disorders are disclosed. In particular, PEG-conjugated dexamethasone compounds and methods of using them for treating inflammatory and autoimmune diseases, including but not limited to lupus, are disclosed.
-
7.发明申请公开(公告)号：US20210252018A1
公开(公告)日：2021-08-19
申请号：US17188309
申请日：2021-03-01
Inventor： Dong Wang , Fang Yuan , Zhenshan Jia , Xiaobei Wang
Abstract: Polyethylene glycol (PEG)-conjugated glucocorticoid prodrugs, methods of preparation, and use for the treatment of diseases and disorders are disclosed. In particular, PEG-conjugated dexamethasone compounds and methods of using them for treating inflammatory and autoimmune diseases, including but not limited to lupus, are disclosed.
-
8.发明申请公开(公告)号：US20180318318A1
公开(公告)日：2018-11-08
申请号：US15775647
申请日：2016-11-12
Inventor： Dong Wang , Fang Yuan , Zhenshan Jia , Xiaobei Wang
CPC classification number: A61K31/57 , A61K9/1075 , A61K47/10 , A61K47/34 , C07J41/0005 , C07J41/0016 , C07J51/00
Abstract: Polyethylene glycol (PEG)-conjugated glucocorticoid prodrugs, methods of preparation, and use for the treatment of diseases and disorders are disclosed. In particular, PEG-conjugated dexamethasone compounds and methods of using them for treating inflammatory and autoimmune diseases, including but not limited to lupus, are disclosed.
-
公开(公告)号：US20150290106A1
公开(公告)日：2015-10-15
申请号：US14436609
申请日：2013-10-17
Inventor： Dong Wang , Zhenshan Jia , Chen Fu
CPC classification number: A61K8/55 , A61K8/34 , A61K31/045 , A61K31/683 , A61K2800/592 , A61Q11/00 , A61Q11/02 , A61K2300/00
Abstract: Compositions and methods for targeting agents, particularly a flavoring, fragrant, or cooling agent such as menthol, to tooth are provided.
Abstract translation: 提供了将针对试剂，特别是调味香料或冷却剂如薄荷醇给牙齿的组合物和方法。
-
公开(公告)号：US20150202313A1
公开(公告)日：2015-07-23
申请号：US14424737
申请日：2013-09-03
Applicant: New York Society for The Ruptured and Crippled Maintaining The Hospital for Special Surgery , Board of Regents of the University of Nebraska
Inventor： Dong Wang , Zhenshan Jia , Yijia Zhang , Steven R. Goldring , Aaron Daluiski
IPC: A61K47/48 , A61K49/00 , A61K31/366
CPC classification number: A61K47/48215 , A61K31/366 , A61K31/74 , A61K47/55 , A61K47/60 , A61K47/6907 , A61K49/00
Abstract: Methods and compositions for treating bone disorders are disclosed.
Abstract translation: 公开了用于治疗骨骼疾病的方法和组合物。
-
-
-
-
-
-
-
-
-
Search Results
10
records
(took 0.025 seconds)
