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1.发明公开公开(公告)号：US20240000800A1
公开(公告)日：2024-01-04
申请号：US18172024
申请日：2023-02-21
发明人： Dong Wang , Fang Yuan , Zhenshan Jia , Xiaobei Wang
CPC分类号： A61K31/57 , C07J41/0016 , C07J41/0005 , A61K9/1075 , A61K47/10 , A61K47/34 , C07J51/00
摘要： Polyethylene glycol (PEG)-conjugated glucocorticoid prodrugs, methods of preparation, and use for the treatment of diseases and disorders are disclosed. In particular, PEG-conjugated dexamethasone compounds and methods of using them for treating inflammatory and autoimmune diseases, including but not limited to lupus, are disclosed.
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2.发明申请公开(公告)号：US20200085842A1
公开(公告)日：2020-03-19
申请号：US16694722
申请日：2019-11-25
发明人： Dong Wang , Fang Yuan , Zhenshan Jia , Xiaobei Wang
摘要： Polyethylene glycol (PEG)-conjugated glucocorticoid prodrugs, methods of preparation, and use for the treatment of diseases and disorders are disclosed. In particular, PEG-conjugated dexamethasone compounds and methods of using them for treating inflammatory and autoimmune diseases, including but not limited to lupus, are disclosed.
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3.发明授权公开(公告)号：US12011450B2
公开(公告)日：2024-06-18
申请号：US18172024
申请日：2023-02-21
发明人： Dong Wang , Fang Yuan , Zhenshan Jia , Xiaobei Wang
CPC分类号： A61K31/57 , A61K9/1075 , A61K47/10 , A61K47/34 , C07J41/0005 , C07J41/0016 , C07J51/00
摘要： Polyethylene glycol (PEG)-conjugated glucocorticoid prodrugs, methods of preparation, and use for the treatment of diseases and disorders are disclosed. In particular, PEG-conjugated dexamethasone compounds and methods of using them for treating inflammatory and autoimmune diseases, including but not limited to lupus, are disclosed.
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4.发明授权公开(公告)号：US11583541B2
公开(公告)日：2023-02-21
申请号：US17188309
申请日：2021-03-01
发明人： Dong Wang , Fang Yuan , Zhenshan Jia , Xiaobei Wang
摘要： Polyethylene glycol (PEG)-conjugated glucocorticoid prodrugs, methods of preparation, and use for the treatment of diseases and disorders are disclosed. In particular, PEG-conjugated dexamethasone compounds and methods of using them for treating inflammatory and autoimmune diseases, including but not limited to lupus, are disclosed.
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5.发明申请公开(公告)号：US20210252018A1
公开(公告)日：2021-08-19
申请号：US17188309
申请日：2021-03-01
发明人： Dong Wang , Fang Yuan , Zhenshan Jia , Xiaobei Wang
摘要： Polyethylene glycol (PEG)-conjugated glucocorticoid prodrugs, methods of preparation, and use for the treatment of diseases and disorders are disclosed. In particular, PEG-conjugated dexamethasone compounds and methods of using them for treating inflammatory and autoimmune diseases, including but not limited to lupus, are disclosed.
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6.发明申请公开(公告)号：US20180318318A1
公开(公告)日：2018-11-08
申请号：US15775647
申请日：2016-11-12
发明人： Dong Wang , Fang Yuan , Zhenshan Jia , Xiaobei Wang
CPC分类号： A61K31/57 , A61K9/1075 , A61K47/10 , A61K47/34 , C07J41/0005 , C07J41/0016 , C07J51/00
摘要： Polyethylene glycol (PEG)-conjugated glucocorticoid prodrugs, methods of preparation, and use for the treatment of diseases and disorders are disclosed. In particular, PEG-conjugated dexamethasone compounds and methods of using them for treating inflammatory and autoimmune diseases, including but not limited to lupus, are disclosed.
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7.发明授权公开(公告)号：US10933071B2
公开(公告)日：2021-03-02
申请号：US16694722
申请日：2019-11-25
发明人： Dong Wang , Fang Yuan , Zhenshan Jia , Xiaobei Wang
摘要： Polyethylene glycol (PEG)-conjugated glucocorticoid prodrugs, methods of preparation, and use for the treatment of diseases and disorders are disclosed. In particular, PEG-conjugated dexamethasone compounds and methods of using them for treating inflammatory and autoimmune diseases, including but not limited to lupus, are disclosed.
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