Invention Grant
- Patent Title: Steviol glycoside transport
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Application No.: US17051299Application Date: 2019-04-29
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Publication No.: US11608364B2Publication Date: 2023-03-21
- Inventor: Johannes Gustaaf Ernst Van Leeuwen , Viktor Marius Boer , Priscilla Zwartjens , Jos Van Vugt , René Marcel De Jong
- Applicant: DSM IP ASSETS B.V.
- Applicant Address: NL Heerlen
- Assignee: DSM IP ASSETS B.V.
- Current Assignee: DSM IP ASSETS B.V.
- Current Assignee Address: NL Heerlen
- Agency: McBee Moore & Vanik IP, LLC
- Priority: EP18170193 20180430
- International Application: PCT/EP2019/060897 WO 20190429
- International Announcement: WO2019/211230 WO 20191107
- Main IPC: C07K14/39
- IPC: C07K14/39 ; C12N9/02 ; C12P19/56

Abstract:
The disclosure provides a recombinant cell capable of producing a steviol glycoside, wherein the cell comprises a nucleic acid coding for a variant of a parent polypeptide, wherein the variant has steviol glycoside transport mediating activity, wherein the variant comprises an amino acid sequence which, when aligned with the amino acid sequence of the parent polypeptide, comprises at least one modification of the amino acid residue corresponding to any of the amino acids in the amino acid sequence of the parent polypeptide, wherein the variant has an improved ability to produce rebaudioside M and optionally other steviol glycosides extracellularly if compared with the parent polypeptide when measured under the same conditions.
Public/Granted literature
- US20210238235A1 STEVIOL GLYCOSIDE TRANSPORT Public/Granted day:2021-08-05
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