- Patent Title: Methods for producing mature adipocytes and methods of use thereof
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Application No.: US16757133Application Date: 2018-10-19
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Publication No.: US11629318B2Publication Date: 2023-04-18
- Inventor: Benjamin D. Pope , Kevin Kit Parker
- Applicant: President and Fellows of Harvard College
- Applicant Address: US MA Cambridge
- Assignee: President and Fellows of Harvard College
- Current Assignee: President and Fellows of Harvard College
- Current Assignee Address: US MA Cambridge
- Agency: McCarter & English, LLP
- Agent Maria Laccotripe Zacharakis; Anita M. Bowles
- International Application: PCT/US2018/056649 WO 20181019
- International Announcement: WO2019/079681 WO 20190425
- Main IPC: C12M3/00
- IPC: C12M3/00 ; A61K35/28 ; C12M1/00 ; C12M1/12 ; C12N5/077
Abstract:
The present invention provides methods and systems which accommodate 3-dimensional adipocyte expansion to produce, e.g., mature adipocytes and synthetic adipose tissue with cellular properties of mature adult organisms, including cell size and cytoarchitecture, and the use of such methods and systems for, e.g., in vitro drug screening and/or toxicity assays, disease modeling, and therapeutic applications.
Public/Granted literature
- US20200248116A1 METHODS FOR PRODUCING MATURE ADIPOCYTES AND METHODS OF USE THEREOF Public/Granted day:2020-08-06
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