Systems and methods are described for managing a supply of building blocks for one or more products. An example method includes: obtaining demand data for each building block from a plurality of building blocks; obtaining substitution data for the plurality of building blocks; providing the demand data and the substitution data as input to a predictive model; receiving as output from the predictive model a predicted optimal production quantity for each building block; and facilitating a production of the plurality of building blocks according to the predicted optimal production quantities.