Invention Grant
- Patent Title: 9-(2-oxacycloalkyl)-9H-purine-2,6-diamine derivatives and their use for the treatment of skin disorders
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Application No.: US16604494Application Date: 2018-04-27
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Publication No.: US11643413B2Publication Date: 2023-05-09
- Inventor: Jana Bibova , Vaclav Mik , Marek Zatloukal , Lucie Plihalova , Jiri Gruz , Lukas Spichal , Karel Dolezal , Miroslav Strnad
- Applicant: UNIVERZITA PALACKEHO V OLOMOUCI
- Applicant Address: CZ Olomouc
- Assignee: UNIVERZITA PALACKEHO V OLOMOUCI
- Current Assignee: UNIVERZITA PALACKEHO V OLOMOUCI
- Current Assignee Address: CZ Olomouc
- Agency: Notaro, Michalos & Zaccaria P.C.
- Priority: CZ 2017237 2017.04.28
- International Application: PCT/CZ2018/050021 2018.04.27
- International Announcement: WO2018/196893A 2018.11.01
- Date entered country: 2019-10-10
- Main IPC: C07D473/16
- IPC: C07D473/16 ; A61K31/505 ; A61K31/52 ; A61K31/22 ; A61Q19/08 ; A61Q19/00 ; A61P17/00 ; A61P25/00 ; A61P35/00 ; A61P37/00 ; A61P39/06 ; A61K8/49
Abstract:
The invention relates to N2,N6-disubstituted-9-(2-oxacycloalkyl)-9H-purine-2, 6-diamine derivatives and their use as drugs and cosmetics. The compounds of the present invention exhibit a number of biological activities associated with oxidative stress inhibition, especially anti-aging, anti-inflammatory and anti-neurodegenerative biological activities. The invention also relates to cosmetic and pharmaceutical compositions containing such derivatives as active agents.
Public/Granted literature
- US20200157105A1 9-(2-OXACYCLOALKYL)-9H-PURINE-2,6-DIAMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF SKIN DISORDERS Public/Granted day:2020-05-21
Information query
