- 专利标题： Immunomodulator compounds
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申请号： US17106309申请日： 2020-11-30
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公开(公告)号： US11708326B2公开(公告)日： 2023-07-25
- 发明人: Christopher Lange , Viengkham Malathong , Venkat Reddy Mali , Jeffrey McMahon , Darren J. McMurtrie , Sreenivas Punna , Howard S. Roth , Rajinder Singh , Yu Wang , Ju Yang , Penglie Zhang
- 申请人： CHEMOCENTRYX, INC.
- 申请人地址： US CA Mountain View
- 专利权人： CHEMOCENTRYX, INC.
- 当前专利权人： CHEMOCENTRYX, INC.
- 当前专利权人地址： US CA Thousand Oaks
- 代理商 Amy C. Madl
- 分案原申请号： US16047545 2018.07.27
- 主分类号： C07D207/12
- IPC分类号： C07D207/12 ; A61K45/06 ; C07D401/12 ; C07D207/267 ; C07D211/44 ; C07D403/12 ; C07D211/38 ; C07D451/06 ; C07D205/12 ; C07F5/02 ; C07D405/14 ; C07D401/14 ; C07D471/10 ; C07D211/76 ; A61P37/02 ; C07D205/04 ; C07D213/85 ; C07D295/088 ; C07D487/10 ; C07D405/12 ; A61K31/40 ; A61K31/4427 ; A61K31/445 ; A61K31/454 ; A61K31/4545 ; C07D211/40 ; C07D211/46
摘要：
Compounds are provided that are useful as immunomodulators. The compounds have the following Formula (I):
including stereoisomers and pharmaceutically acceptable salts thereof, wherein Z, L, R1a, R1b, R1c, R1d, R2a, R2b, R2c, R3, R4, R5, R6a, R6b, m and n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
including stereoisomers and pharmaceutically acceptable salts thereof, wherein Z, L, R1a, R1b, R1c, R1d, R2a, R2b, R2c, R3, R4, R5, R6a, R6b, m and n are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
公开/授权文献
- US20210147356A1 IMMUNOMODULATOR COMPOUNDS 公开/授权日：2021-05-20
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