A device for detection of tetrahydrocannabinol or THC in a sample includes a sensor including a substrate and a sensor medium on the substrate. The sensor medium includes at least one nanostructure, wherein at least one property of the sensor medium is dependent upon the presence of THC on a surface of the sensor medium. The device further includes electronic circuitry including at least one measurement system in operative connection with the sensor to measure a variable relatable to the at least one property of the sensor medium dependent upon the presence of THC.