公开(公告)号：US12109519B2

公开(公告)日：2024-10-08

申请号：US16900682

申请日：2020-06-12

申请人： Utah Valley University

发明人： Timothy Edwin Doyle

IPC分类号： B01L3/00 ,  A61B5/00 ,  A61B5/08 ,  A61B5/1468 ,  A61B5/1477 ,  A61M15/00 ,  A61M15/02 ,  A61M16/10 ,  A62B23/02 ,  B01D39/16 ,  B01F23/00 ,  B01F23/41 ,  B01F101/23 ,  B23Q17/24 ,  C07K14/705 ,  C12M1/34 ,  C12Q1/04 ,  C12Q1/18 ,  C12Q1/686 ,  G01N21/3577 ,  G01N21/359 ,  G01N21/39 ,  G01N21/45 ,  G01N21/64 ,  G01N27/414 ,  G01N30/12 ,  G01N30/68 ,  G01N30/70 ,  G01N30/72 ,  G01N30/88 ,  G01N33/00 ,  G01N33/18 ,  G01N33/50 ,  G01N33/53 ,  G01N33/543 ,  G01N33/68 ,  G01N33/74 ,  H10K10/46 ,  H10K85/00 ,  H10K85/20

CPC分类号： B01D39/1623 ,  A61B5/1468 ,  A61B5/1477 ,  A61B5/6803 ,  A61M15/0001 ,  A61M15/02 ,  A61M16/105 ,  A62B23/025 ,  A61B5/082 ,  A61M2205/0244 ,  A61M2205/0294 ,  A61M2205/18 ,  A61M2205/3303 ,  A61M2205/7536 ,  B01D2239/0414

摘要： Disclosed herein is a molecular imprinted protective face mask comprising a supportive structure, a surface material that receives and retains a molecular imprint and that is positioned to contact airborne molecules during use, a molecular imprint of a bioactive molecule wherein an imprinted cavity is at least one of a bioactive molecule with a molecular configuration that captures a specific airborne and/or microdroplet-borne molecule and a protein with a binding site that captures a specific molecule.

公开(公告)号：US20240315613A1

公开(公告)日：2024-09-26

申请号：US18187390

申请日：2023-03-21

申请人： Know Labs, Inc.

发明人： John CRONIN

IPC分类号： A61B5/145 ,  A61B5/00 ,  A61B5/1477

CPC分类号： A61B5/14546 ,  A61B5/1477 ,  A61B5/4839 ,  A61B5/7246 ,  A61B5/742

摘要： A system which includes an apparatus for generating radio frequency scanning data which includes a transmitter for transmitting radio waves below the skin surface of a person and a two-dimensional array of receive antennas for receiving the radio waves, including a reflected portion of the transmitted radio waves that is reflected from a blood vessel of the person. The transmitter includes at least two different polarization orientations and the receive antennas have polarization orientations that correspond to the transmit antennas. The wave signal is compared to known standard waveforms, and similar waveforms are input into a machine learning algorithm to determine one or more health parameters of the person. The health parameters are recorded and may be later synchronized with a video recording. Alerts may warn health professionals when parameters are outside normal range. The health parameters may be used to direct a device.

公开(公告)号：US12076144B2

公开(公告)日：2024-09-03

申请号：US17944039

申请日：2022-09-13

申请人： KHN Solutions, LLC

发明人： Keith Harry Nothacker ,  Will Tammen ,  Imraan Aziz

IPC分类号： A61B5/1477 ,  A61B5/00 ,  A61B5/08 ,  A61B5/145 ,  A61B5/18 ,  A61B10/00 ,  G01N27/416 ,  G01N33/497 ,  G16Z99/00 ,  A61B5/097

CPC分类号： A61B5/1477 ,  A61B5/082 ,  A61B5/14546 ,  A61B5/18 ,  A61B5/4023 ,  A61B5/4845 ,  A61B5/4863 ,  A61B5/681 ,  A61B5/7275 ,  A61B10/0064 ,  G01N27/416 ,  G01N33/4972 ,  G16Z99/00 ,  A61B5/0022 ,  A61B5/097 ,  A61B5/486 ,  A61B5/7282 ,  A61B2010/0009 ,  A61B2503/22 ,  A61B2562/0219

摘要： A system for transdermal alcohol sensing to be worn near a skin surface of a user, including: an alcohol sensor; a microporous membrane; a housing coupled to the alcohol sensor and the membrane, defining a volume between the alcohol sensor and a first membrane side, and fluidly isolating the volume from a second membrane side opposing the first membrane side; an electronics subsystem electrically coupled to the alcohol sensor, operable to power and receive signals from the alcohol sensor; and a fastener operable to position the second membrane side proximal the skin surface.

公开(公告)号：US12076143B2

公开(公告)日：2024-09-03

申请号：US16124164

申请日：2018-09-06

申请人： EnLiSense LLC ,  Board of Regents, The University of Texas System

发明人： Shalini Prasad ,  Sriram Muthukumar

IPC分类号： A61B5/1477 ,  A61B5/145 ,  A61B5/00

CPC分类号： A61B5/1477 ,  A61B5/14517 ,  A61B5/0002 ,  A61B5/6833

摘要： A biosensor device includes a porous substrate, where the substrate comprises semiconductor elements functionalized to conjugate with a particular analyte, the semiconductor elements are embedded within at least a portion of the substrate, and the substrate is to absorb fluid capable of carrying the particular analyte. The device further includes two or more electrodes attached to the substrate to correspond to the portion of the substrate, where the portion of the substrate further comprises Room-Temperature Ionic Liquid (RTIL).

公开(公告)号：US20240180460A1

公开(公告)日：2024-06-06

申请号：US18442924

申请日：2024-02-15

申请人： Dexcom, Inc.

发明人： Apurv U. Kamath ,  John Michael Dobbles ,  Aarthi Mahalingam

IPC分类号： A61B5/1477 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/1495

CPC分类号： A61B5/1477 ,  A61B5/0004 ,  A61B5/14532 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/6833 ,  A61B5/7203 ,  A61B5/725 ,  A61B5/7264 ,  A61B5/7275 ,  A61B5/7278 ,  A61B5/742 ,  A61B5/743

摘要： Systems and methods for processing sensor data are provided. In some embodiments, systems and methods are provided for calibration of a continuous analyte sensor. In some embodiments, systems and methods are provided for classification of a level of noise on a sensor signal. In some embodiments, systems and methods are provided for determining a rate of change for analyte concentration based on a continuous sensor signal. In some embodiments, systems and methods for alerting or alarming a patient based on prediction of glucose concentration are provided.

公开(公告)号：US11903707B2

公开(公告)日：2024-02-20

申请号：US17692613

申请日：2022-03-11

申请人： Purdue Research Foundation

发明人： Robert Graham Cooks ,  Zheng Ouyang ,  Chien-hsun Chen ,  Ziqing Lin ,  Livia Schiavinato Eberlin

IPC分类号： A61B5/1477 ,  A61B10/00 ,  H01J49/04 ,  A61M11/00 ,  A61M25/00 ,  H01J49/00 ,  H01J49/16 ,  H01J49/34 ,  G01N33/483 ,  A61B5/145 ,  A61B5/15 ,  A61B5/157 ,  G01N1/02

CPC分类号： A61B5/1477 ,  A61B10/0045 ,  A61M11/00 ,  A61M25/00 ,  G01N33/4833 ,  H01J49/0022 ,  H01J49/0404 ,  H01J49/0445 ,  H01J49/167 ,  H01J49/34 ,  A61B5/145 ,  A61B5/1405 ,  A61B5/157 ,  A61B5/150015 ,  A61B5/150992 ,  A61M2202/0468 ,  G01N2001/028

摘要： The invention generally relates to enclosed desorption electrospray ionization probes, systems, and methods. In certain embodiments, the invention provides a source of DESI-active spray, in which a distal portion of the source is enclosed within a transfer member such that the DESI-active spray is produced within the transfer member.

公开(公告)号：US11712200B2

公开(公告)日：2023-08-01

申请号：US16608096

申请日：2018-04-26

申请人： University of Pittsburgh—Of the Commonwealth System of Higher Education

发明人： Alexander Star ,  Sean Hwang

IPC分类号： A61B5/08 ,  A61B5/00 ,  C01B32/159 ,  C01B32/198 ,  A61B5/097 ,  A61B5/1455 ,  A61B5/1477 ,  G01N33/94

CPC分类号： A61B5/4845 ,  A61B5/082 ,  A61B5/097 ,  A61B5/1455 ,  A61B5/1477 ,  C01B32/159 ,  C01B32/198 ,  G01N33/948 ,  A61B2562/0285

摘要： A device for detection of tetrahydrocannabinol or THC in a sample includes a sensor including a substrate and a sensor medium on the substrate. The sensor medium includes at least one nanostructure, wherein at least one property of the sensor medium is dependent upon the presence of THC on a surface of the sensor medium. The device further includes electronic circuitry including at least one measurement system in operative connection with the sensor to measure a variable relatable to the at least one property of the sensor medium dependent upon the presence of THC.

公开(公告)号：US20230233113A1

公开(公告)日：2023-07-27

申请号：US18129707

申请日：2023-03-31

申请人： SENSILL, INC.

发明人： Mitchell Levinson ,  Ardeshir Bayat ,  Richard Hatch ,  Scott West ,  William Shea

IPC分类号： A61B5/145 ,  G01N21/78 ,  A61B5/1477 ,  A61B5/00

CPC分类号： A61B5/14546 ,  G01N21/78 ,  A61B5/1477 ,  A61B5/6832 ,  A61B5/6831 ,  A61B5/14507 ,  A61B2562/046 ,  A61B2562/164 ,  A61B2562/168

摘要： Detection devices, systems, and methods include those for detecting analytes (e.g., volatile organic compounds (VOCs) and/or other chemical substances) from a target area of a subject's anatomy (e.g., a subject's skin, a wound on a subject, etc.). In some cases, a detector may have a detecting component that includes an analyte sensitive material applied to a substrate. The detector may be used with a pump. The detector may include a hydrophobic, gas permeable material configured to limit liquid reaching the analyte sensitive material, while allowing analytes in gaseous fluid to reach the analyte sensitive material.

公开(公告)号：US11666253B2

公开(公告)日：2023-06-06

申请号：US16796920

申请日：2020-02-20

申请人： ASCENSIA DIABETES CARE HOLDINGS AG

发明人： Juergen J. Zach ,  Daniel V. Brown

IPC分类号： A61B5/145 ,  A61B5/1477 ,  A61B5/00 ,  G01N33/66 ,  G06F1/16 ,  G06F17/14 ,  A61B5/1473 ,  G01N31/00 ,  H04Q9/00

CPC分类号： A61B5/14532 ,  A61B5/002 ,  A61B5/1451 ,  A61B5/1473 ,  A61B5/1477 ,  A61B5/6847 ,  A61B5/7207 ,  A61B5/7225 ,  A61B5/7253 ,  A61B5/7257 ,  A61B5/742 ,  G01N31/005 ,  G01N33/66 ,  G06F1/163 ,  G06F17/142 ,  H04Q9/00 ,  H04Q2209/40

摘要： Continuous glucose monitoring (CGM) may include applying a periodic excitation signal via an electrode of a CGM sensor to human interstitial fluid to drive an oxidation/reduction reaction, and measuring the current through the electrode. In some embodiments, the measured current is sampled and digitized, and various harmonics of the excitation signal's fundamental frequency are extracted. A set of relationships of at least two harmonics each is generated from the spectral amplitudes of a set of pairs, triplets, etc., of the harmonics, and the set of relationships is mapped to a glucose concentration such as based on the contents of a harmonic relationship database having a pre-existing set of harmonic relationships and glucose concentrations to which those sets of harmonic relationships correspond, for example. Numerous other embodiments are provided.

公开(公告)号：US11638542B2

公开(公告)日：2023-05-02

申请号：US16796920

申请日：2020-02-20

申请人： ASCENSIA DIABETES CARE HOLDINGS AG

发明人： Juergen J. Zach ,  Daniel V. Brown

IPC分类号： A61B5/145 ,  A61B5/1477 ,  A61B5/00 ,  G01N33/66 ,  G06F1/16 ,  G06F17/14 ,  A61B5/1473 ,  G01N31/00 ,  H04Q9/00

摘要： Continuous glucose monitoring (CGM) may include applying a periodic excitation signal via an electrode of a CGM sensor to human interstitial fluid to drive an oxidation/reduction reaction, and measuring the current through the electrode. In some embodiments, the measured current is sampled and digitized, and various harmonics of the excitation signal's fundamental frequency are extracted. A set of relationships of at least two harmonics each is generated from the spectral amplitudes of a set of pairs, triplets, etc., of the harmonics, and the set of relationships is mapped to a glucose concentration such as based on the contents of a harmonic relationship database having a pre-existing set of harmonic relationships and glucose concentrations to which those sets of harmonic relationships correspond, for example. Numerous other embodiments are provided.