- 专利标题： Method of culturing segmented filamentous bacteria in vitro
-
申请号： US16548280申请日： 2019-08-22
-
公开(公告)号： US11725183B2公开(公告)日： 2023-08-15
- 发明人: Gerard Eberl , David Bikard , Pamela Schnupf , Nadine Cerf Bensussan , Valerie Gaboriau-Routhiau , Philippe Sansonetti
- 申请人： INSTITUT PASTEUR , FONDATION IMAGINE , ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS , UNIVERSITE PARIS DESCARTES , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (IN-SERM)
- 申请人地址： FR Paris
- 专利权人： INSTITUT PASTEUR,FONDATION IMAGINE,ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS,UNIVERSITE PARIS CITE,INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
- 当前专利权人： INSTITUT PASTEUR,FONDATION IMAGINE,ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS,UNIVERSITE PARIS CITE,INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
- 当前专利权人地址： FR Paris; FR Paris; FR Paris; FR Paris; FR Paris
- 代理机构： Arrigo, Lee, Guttman & Mouta-Bellum LLP
- 优先权： WO TIB2014067285 2014.12.23
- 主分类号： C12N1/20
- IPC分类号： C12N1/20 ; C12N15/74 ; C12N13/00
摘要：
The present invention relates to an in vitro method of culturing a segmented filamentous bacterium strain, comprising co-culturing said segmented filamentous bacterium strain with a eukaryotic host cell, wherein the culture is performed at an O2 level inferior to 5% in a rich tissue culture liquid medium containing bacterial medium components including iron. The present invention also relates to methods for genetically modifying a segmented filamentous bacterium strain comprising a step a culturing the strain in vitro.
信息查询
IPC分类:
