Invention Grant
- Patent Title: Method and apparatus for low coherence interferometry
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Application No.: US16719305Application Date: 2019-12-18
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Publication No.: US11751762B2Publication Date: 2023-09-12
- Inventor: Jongsik Kim , Ying Dong , Song Mei , Kinpui Chan , Zhenguo Wang , Zaixing Mao
- Applicant: Topcon Corporation
- Applicant Address: JP Tokyo
- Assignee: TOPCON CORPORATION
- Current Assignee: TOPCON CORPORATION
- Current Assignee Address: JP Tokyo
- Agency: Pearne & Gordon LLP
- Main IPC: A61B3/10
- IPC: A61B3/10 ; A61B3/14 ; A61B3/12 ; G01N21/17

Abstract:
A low coherence imaging method comprises acquiring image data of an object with an interferometric imaging system, where the image data is from a location of the object at first and second times; determining a first depth profile from the image data from the location at the first time and a second depth profile from the image data of the location at the second time; determining a change with respect to depth between the first and second depth profiles; and determining a property, or identifying a location, of at least one dynamic particle in the object based on the change between the first and second depth profiles. The method is able to identify, analyze, and/or visualize dynamic particles with features comparable to at least fluorescein angiography, indocyanine green angiography, confocal scanning laser fluorescein angiography, confocal scanning laser indocyanine green angiography, and fluorescence microscopy images, without the use of a dye.
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