公开(公告)号：US11751762B2

公开(公告)日：2023-09-12

申请号：US16719305

申请日：2019-12-18

Applicant: Topcon Corporation

Inventor： Jongsik Kim ,  Ying Dong ,  Song Mei ,  Kinpui Chan ,  Zhenguo Wang ,  Zaixing Mao

IPC: A61B3/10 ,  A61B3/14 ,  A61B3/12 ,  G01N21/17

CPC classification number: A61B3/102 ,  A61B3/1225 ,  A61B3/14 ,  G01N21/17 ,  G01N2021/1787

Abstract: A low coherence imaging method comprises acquiring image data of an object with an interferometric imaging system, where the image data is from a location of the object at first and second times; determining a first depth profile from the image data from the location at the first time and a second depth profile from the image data of the location at the second time; determining a change with respect to depth between the first and second depth profiles; and determining a property, or identifying a location, of at least one dynamic particle in the object based on the change between the first and second depth profiles. The method is able to identify, analyze, and/or visualize dynamic particles with features comparable to at least fluorescein angiography, indocyanine green angiography, confocal scanning laser fluorescein angiography, confocal scanning laser indocyanine green angiography, and fluorescence microscopy images, without the use of a dye.

公开(公告)号：US11361481B2

公开(公告)日：2022-06-14

申请号：US16574453

申请日：2019-09-18

Applicant: Topcon Corporation

Inventor： Song Mei ,  Zaixing Mao ,  Ying Dong ,  Zhenguo Wang ,  Kinpui Chan

IPC: G06T11/00 ,  G06T7/11 ,  G06T5/20 ,  G06T7/00

Abstract: Shadows caused by opacities and obstructions (such as blood vessels) can block detection of structural information of objects below the shadow-causing structure, affecting visualization and analysis of those deeper structures. An image processing method for removing these shadows includes applying a low pass filter to an energy profile of an image to remove high frequency fluctuations in energy, thereby effectively recovering lower energy inside shadow regions and removing high frequency speckle. The image is then adjusted, for example by linear scaling, based on the filtered energy profile. Two dimensional filters may also be applied for volumes.

公开(公告)号：US20210082163A1

公开(公告)日：2021-03-18

申请号：US16574453

申请日：2019-09-18

Applicant: Topcon Corporation

Inventor： Song Mei ,  Zaixing Mao ,  Ying Dong ,  Zhenguo Wang ,  Kinpui Chan

IPC: G06T11/00 ,  G06T7/00 ,  G06T5/20 ,  G06T7/11

Abstract: Shadows caused by opacities and obstructions (such as blood vessels) can block detection of structural information of objects below the shadow-causing structure, affecting visualization and analysis of those deeper structures. An image processing method for removing these shadows includes applying a low pass filter to an energy profile of an image to remove high frequency fluctuations in energy, thereby effectively recovering lower energy inside shadow regions and removing high frequency speckle. The image is then adjusted, for example by linear scaling, based on the filtered energy profile. Two dimensional filters may also be applied for volumes.