A configurable interface circuit is disclosed. An integrated circuit (IC) having a particular configuration. The IC includes a memory system and a communication fabric coupled to the memory system. The IC further includes a plurality of agent circuits configured to make requests to the memory system that are in a first format that is not specific to the particular configuration of the IC. A plurality of interface circuits is coupled between corresponding ones of the plurality of agent circuits and the communication fabric. A given one of the plurality of interface circuits is configured to receive a request to the memory system in the first format and output the request in a second format that is specific to the particular configuration of the IC.