Invention Grant
- Patent Title: Method and sensor for detecting L-arginine
-
Application No.: US16969588Application Date: 2019-12-31
-
Publication No.: US11761922B2Publication Date: 2023-09-19
- Inventor: Zhong Cao , Ningtao Zhou , Li Zhou , Qin Zhu , Jinglin He , Zhongliang Xiao , Yumin He , Zemeng Feng , Yulong Yin
- Applicant: CHANGSHA UNIVERSITY OF SCIENCE AND TECHNOLOGY
- Applicant Address: CN Changsha
- Assignee: CHANGSHA UNIVERSITY OF SCIENCE AND TECHNOLOGY
- Current Assignee: CHANGSHA UNIVERSITY OF SCIENCE AND TECHNOLOGY
- Current Assignee Address: CN Changsha
- Agency: Bayramoglu Law Offices LLC
- Priority: CN 1910604859.6 2019.07.05
- International Application: PCT/CN2019/130232 2019.12.31
- International Announcement: WO2021/004039A 2021.01.14
- Date entered country: 2020-08-13
- Main IPC: G01N27/327
- IPC: G01N27/327 ; C07K1/107 ; G01N27/48

Abstract:
A method and a sensor for detecting L-arginine are provided. The method includes synthesizing ferrocene-functionalized hexadecapeptide dithiocyclopentane (FC-P16 Peptide), preparing a polypeptide composite membrane-modified electrode (FC-P16 Peptide/AuE), detecting L-Arg and other steps. The results show that the polypeptide composite membrane-modified electrode (FC-P16 Peptide/AuE) exhibits excellent electrochemical response properties to L-Arg. In 10 mmol/L phosphate-buffered saline (PBS, pH=7.4), the DPV response peak current of the polypeptide composite membrane-modified electrode has an excellent linear relationship with the L-Arg concentration of 1.0×10−13 mol/L to 1.0×10−7 mol/L, with a detection limit of 1.0×10−13 mol/L. With prominent reproducibility, repeatability and selectivity, the modified electrode has potential application in life science and nutritional health.
Public/Granted literature
- US20230101196A1 METHOD AND SENSOR FOR DETECTING L-ARGININE Public/Granted day:2023-03-30
Information query