Invention Grant
- Patent Title: Body fluid resistant tissue adhesives
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Application No.: US17110841Application Date: 2020-12-03
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Publication No.: US11884845B2Publication Date: 2024-01-30
- Inventor: Xuanhe Zhao , Hyunwoo Yuk , Xinyu Mao , Christoph Nabzdyk
- Applicant: Massachusetts Institute of Technology , Mayo Foundation for Medical Education and Research
- Applicant Address: US MA Cambridge
- Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY,MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
- Current Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY,MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
- Current Assignee Address: US MA Cambridge; US MN Rochester
- Agency: Nieves IP Law Group, LLC
- Agent Peter A. Nieves
- Main IPC: C09J105/08
- IPC: C09J105/08 ; C09J133/02 ; A61L24/00 ; C09J11/06 ; C09J9/00 ; C09J151/00

Abstract:
A tissue adhesive material that provides fast and robust adhesion even on tissue surfaces covered in bodily fluids. The tissue adhesive material is formed of a hydrophobic matrix and a plurality of bioadhesive microparticles dispersed within the hydrophobic matrix configured such that disposing the adhesive material directly on a fluid covered surface and applying pressure causes the (a) hydrophobic matrix to repel the fluid, (b) the bioadhesive particles to compress forming an adhesive layer, and (c) the bioadhesive particles to form temporary crosslinks followed by covalent crosslinks with the surface.
Public/Granted literature
- US20210163797A1 BODY FLUID RESISTANT TISSUE ADHESIVES Public/Granted day:2021-06-03
Information query
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